Description

CelCradle™ Benchtop bioreactor

Cradle for your Adherent Cells

CelCradle is a bench-scale bioreactor system that can support high adherent cell density culture. It is a single-use, cost effective packed-bed bioreactor system for adherent scale-up from laboratory scale to production scale. This disposable bioreactor fits inside a 6ft3 CO2 incubator (for batch culture) or 8.5ft3 CO2 incubator (for perfusion culture).

The ready-to-use bottles, as part of single-use manufacturing, helps eliminate validation costs as compared to multiple-use system when starting on your next cell culture run. The system components come pre-sterilized, pre-packed that speed up your research whether for vaccine, stem cell, or viral production applications.

Features

• SS 316 L Carcass for easy cleaning
• Compact and easy-to-install, small footprint benchtop design
• Pre-sterilized, ready-to-use, disposable bottles
• Conductive Environment
• Culture cells with an environment of extremely low shear stress, foam-free, and no O2 limitation
• Compatible with most serum-free media
• Macroporous Carriers’ Surface
• to grow most anchorage-dependent cells and allow easy harvest of whole cells, cell components, or secreted proteins
• Provides large surface area of up to 15,000 cm2 per bottle for adherent cell growth
• Capacity to produce hundreds of milligrams to several grams of secreted proteins or monoclonal antibodies per month in four bottles
• Few parameters for easy optimization
• Culture in batch, fed-batch, or recirculation modes
• Scale-up through TideXcell pilot scale bioreactor or through directly multiplying number of bottles used

Applications

• Mammalian and Insect Cell Culture
• Monoclonal Antibody Production
• Gene and Cell Therapy (autologous)
• Viral Vector production
• Pharmacokinetics Study
• Vaccine Production
• Drug Discovery
• Protein Production
• Proteome Research